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Pharmacologic Suppression of Inflammation by a Diphenyldifluoroketone, EF24, in a Rat Model of Fixed-Volume Hemorrhage Improves Survival

An exaggerated release of proinflammatory cytokines and accompanying inflammation contributes to the development of multiple organ failure after hemorrhagic shock. Here, we tested the nuclear factor (NF) κ-light-chain-enhancer of activated B cell (NF-κB)–mediated transcriptional control of inflammat...

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Detalhes bibliográficos
Main Authors: Yadav, Vivek R., Sahoo, Kaustuv, Roberts, Pamela R., Awasthi, Vibhudutta
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807066/
https://ncbi.nlm.nih.gov/pubmed/23995597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.208009
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