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Base triplet stepping by the Rad51/RecA family of recombinases
DNA strand exchange plays a central role in genetic recombination across all kingdoms of life, but the physical basis for these reactions remains poorly defined. Using single-molecule imaging, we found that bacterial RecA and eukaryotic Rad51 and Dmc1 all stabilize strand exchange intermediates in p...
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| Pubblicato in: | Science |
|---|---|
| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4580133/ https://ncbi.nlm.nih.gov/pubmed/26315438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab2666 |
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