Base triplet stepping by the Rad51/RecA family of recombinases

DNA strand exchange plays a central role in genetic recombination across all kingdoms of life, but the physical basis for these reactions remains poorly defined. Using single-molecule imaging, we found that bacterial RecA and eukaryotic Rad51 and Dmc1 all stabilize strand exchange intermediates in p...

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Bibliographic Details
Published in:Science
Main Authors: Lee, Ja Yil, Terakawa, Tsuyoshi, Qi, Zhi, Steinfeld, Justin B., Redding, Sy, Kwon, YoungHo, Gaines, William A., Zhao, Weixing, Sung, Patrick, Greene, Eric C.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580133/
https://ncbi.nlm.nih.gov/pubmed/26315438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab2666
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