Endogenously Generated Omega‐3 Fatty Acids Attenuate Vascular Inflammation and Neointimal Hyperplasia by Interaction With Free Fatty Acid Receptor 4 in Mice

BACKGROUND: Omega‐3 polyunsaturated fatty acids (ω3 PUFAs) suppress inflammation through activation of free fatty acid receptor 4 (FFAR4), but this pathway has not been explored in the context of cardiovascular disease. We aimed to elucidate the involvement of FFAR4 activation by ω3 PUFAs in the pro...

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Pubblicato in:J Am Heart Assoc
Autori principali: Li, Xinzhi, Ballantyne, Laurel L., Che, Xinghui, Mewburn, Jeffrey D., Kang, Jing X., Barkley, Robert M., Murphy, Robert C., Yu, Ying, Funk, Colin D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2015
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579939/
https://ncbi.nlm.nih.gov/pubmed/25845931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.001856
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