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Liposomal Simvastatin Attenuates Neointimal Hyperplasia in Rats

Monocytes, macrophages, and inflammation play a key role in the process of neointimal proliferation and restenosis. The present study evaluated whether systemic and transient depletion of monocytes could be obtained by a single intravenous (IV) injection of simvastatin liposomes, for the inhibition...

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Main Authors: Afergan, Eyal, Ben David, Meital, Epstein, Hila, Koroukhov, Nickolay, Gilhar, Dalia, Rohekar, Keren, Danenberg, Haim D., Golomb, Gershon
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844514/
https://ncbi.nlm.nih.gov/pubmed/20143196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9173-5
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