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Could valproic acid be an effective anticancer agent? The evidence so far

Valproic acid is an inhibitor of class I histone deacetylases. Epigenetic therapies in cancer have been focus of a keen interest and HDAC inhibitors in particular have been approved for certain types of hematologic malignancies. Valproic acid is an attractive candidate for cancer therapy due to its...

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Detalles Bibliográficos
Publicado en:Expert Rev Anticancer Ther
Autores principales: Brodie, Seth A, Brandes, Johann C
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579528/
https://ncbi.nlm.nih.gov/pubmed/25017212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.2014.940329
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