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Long-term use of valproic acid in United States Veterans associates with reduced risk of smoking related head-and neck cancer
PURPOSE: Epigenetic events play a major role in the carcinogenesis of tobacco-related cancers. We conducted a retrospective cohort study to evaluate the effects of exposure to the anti-convulsant agent valproic acid (VPA), a HDAC inhibitor, on the risk for cancers of the lung, head and neck, prostat...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4102261/ https://ncbi.nlm.nih.gov/pubmed/24664792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28479 |
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