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Could valproic acid be an effective anticancer agent? The evidence so far

Valproic acid is an inhibitor of class I histone deacetylases. Epigenetic therapies in cancer have been focus of a keen interest and HDAC inhibitors in particular have been approved for certain types of hematologic malignancies. Valproic acid is an attractive candidate for cancer therapy due to its...

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Detalhes bibliográficos
Publicado no:Expert Rev Anticancer Ther
Main Authors: Brodie, Seth A, Brandes, Johann C
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579528/
https://ncbi.nlm.nih.gov/pubmed/25017212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.2014.940329
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