HLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma

BACKGROUND: Tumour cells can evade the immune system by dysregulation of human leukocyte antigens (HLA-I). Low quantity and/or altered quality of HLA-I cell surface expression is the result of either HLA-I alterations or dysregulations of proteins of the antigen-processing machinery (APM). Tapasin i...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Thuring, Camilla, Follin, Elna, Geironson, Linda, Freyhult, Eva, Junghans, Victoria, Harndahl, Mikkel, Buus, Søren, Paulsson, Kajsa M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578088/
https://ncbi.nlm.nih.gov/pubmed/26313662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.297
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