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Real-time, High-Throughput Measurements of Peptide-MHC-I Dissociation Using a Scintillation Proximity Assay

Efficient presentation of peptide-MHC class I complexes to immune T cells depends upon stable peptide-MHC class I interactions. Theoretically, determining the rate of dissociation of a peptide-MHC class I complexes is straightforward; in practical terms, however, generating the accurate and closely...

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Detalhes bibliográficos
Publicado no:J Immunol Methods
Main Authors: Harndahl, Mikkel, Rasmussen, Michael, Roder, Gustav, Buus, Søren
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341823/
https://ncbi.nlm.nih.gov/pubmed/21044632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2010.10.012
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