SYNERGISM OF TAPASIN AND HLA IN RESOLVING HCV INFECTION

CD8+ T cell responses to hepatitis C virus (HCV) are important in generating a successful immune response and spontaneously clearing infection. HLA class I presents viral peptides to CD8+ T cells to permit detection of infected cells, and tapasin is an important component of the peptide loading comp...

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Main Authors: Ashraf, Shirin, Nitschke, Katja, Warshow, Usama M, Brooks, Collin R, Kim, Arthur Y, Lauer, Georg M, Hydes, Theresa J, Cramp, Matthew E, Alexander, Graeme, Little, Ann-Margaret, Thimme, Robert, Neumann-Haefelin, Christoph, Khakoo, Salim I
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759612/
https://ncbi.nlm.nih.gov/pubmed/23532923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26415
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