ADAM10: a new player in breast cancer progression?

BACKGROUND: The ADAM proteases are best known for their role in shedding the extracellular domain of transmembrane proteins. Among the transmembrane proteins shed by ADAM10 are notch, HER2, E-cadherin, CD44, L1 and the EGFR ligands, EGF and betacellulin. As cleavage of several of these proteins has...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Cancer
Main Authors: Mullooly, Maeve, McGowan, Patricia M, Kennedy, Susan A, Madden, Stephen F, Crown, John, O' Donovan, Norma, Duffy, Michael J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Molecular Diagnostics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578086/
https://ncbi.nlm.nih.gov/pubmed/26284334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.288
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