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Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy

Spinal and bulbar muscular atrophy (SBMA) is a progressive neuromuscular disease caused by polyglutamine expansion in the androgen receptor (AR) protein. Despite extensive research, the exact pathogenic mechanisms underlying SBMA remain elusive. In this study, we present evidence that Nemo-like kina...

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Veröffentlicht in:eLife
Hauptverfasser: Todd, Tiffany W, Kokubu, Hiroshi, Miranda, Helen C, Cortes, Constanza J, La Spada, Albert R, Lim, Janghoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577982/
https://ncbi.nlm.nih.gov/pubmed/26308581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08493
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