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Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy

Spinal and bulbar muscular atrophy (SBMA) is a progressive neuromuscular disease caused by polyglutamine expansion in the androgen receptor (AR) protein. Despite extensive research, the exact pathogenic mechanisms underlying SBMA remain elusive. In this study, we present evidence that Nemo-like kina...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Todd, Tiffany W, Kokubu, Hiroshi, Miranda, Helen C, Cortes, Constanza J, La Spada, Albert R, Lim, Janghoo
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577982/
https://ncbi.nlm.nih.gov/pubmed/26308581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08493
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