Human Cytotoxic T Lymphocyte-Mediated Acute Liver Failure and Rescue by Immunoglobulin in Human Hepatocyte Transplant TK-NOG Mice

Hepatitis B virus (HBV)-specific cytotoxic T lymphocytes (CTLs) are critical in eliminating infection. We developed an animal model in which HBV-infected human hepatocytes are targeted by HBV-specific CTLs. After HBV inoculation in human hepatocyte-transplanted herpes simplex virus type-1 thymidine...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Uchida, Takuro, Hiraga, Nobuhiko, Imamura, Michio, Tsuge, Masataka, Abe, Hiromi, Hayes, C. Nelson, Aikata, Hiroshi, Ishida, Yuji, Tateno, Chise, Yoshizato, Katsutoshi, Ohdan, Hideki, Murakami, Kazunari, Chayama, Kazuaki
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577899/
https://ncbi.nlm.nih.gov/pubmed/26246560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01126-15
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