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Alteration of Mature Nucleocapsid and Enhancement of Covalently Closed Circular DNA Formation by Hepatitis B Virus Core Mutants Defective in Complete-Virion Formation

Assembly of hepatitis B virus (HBV) begins with packaging of the pregenomic RNA (pgRNA) into immature nucleocapsids (NC), which are converted to mature NCs containing the genomic relaxed circular (RC) DNA as a result of reverse transcription. Mature NCs have two alternative fates: (i) envelopment by...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Cui, Xiuji, Luckenbaugh, Laurie, Bruss, Volker, Hu, Jianming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577893/
https://ncbi.nlm.nih.gov/pubmed/26202253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01481-15
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