Cysteinyl leukotrienes mediate lymphokine killer activity induced by NKG2D and IL-15 in cytotoxic T cells during celiac disease

Eicosanoids are inflammatory mediators that play a key but incompletely understood role in linking the innate and adaptive immune systems. Here, we show that cytotoxic effector T cells (CTLs) are capable of both producing and responding to cysteinyl leukotrienes (CystLTs), allowing for the killing o...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Tang, Fangming, Sally, Benjamin, Lesko, Kathryn, Discepolo, Valentina, Abadie, Valerie, Ciszewski, Cezary, Semrad, Carol, Guandalini, Stefano, Kupfer, Sonia S., Jabri, Bana
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2015
Matèries:
Brief Definitive Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577841/
https://ncbi.nlm.nih.gov/pubmed/26304964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150303
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