Cytosolic PLA(2) is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15

IL-15 and NKG2D promote autoimmunity and celiac disease by arming cytotoxic T lymphocytes (CTLs) to cause tissue destruction. However, the downstream signaling events underlying these functional properties remain unclear. Here, we identify cytosolic phospholipase A(2) (cPLA(2)) as a central molecule...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Tang, Fangming, Chen, Zhangguo, Ciszewski, Cezary, Setty, Mala, Solus, Jason, Tretiakova, Maria, Ebert, Ellen, Han, Jin, Lin, Anning, Guandalini, Stefano, Groh, Veronika, Spies, Thomas, Green, Peter, Jabri, Bana
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2009
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699120/
https://ncbi.nlm.nih.gov/pubmed/19237603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071887
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים