Distinct and Synergistic Contributions of Epithelial Stress and Adaptive Immunity to Functions of Intraepithelial Killer Cells and Active Celiac Disease

BACKGROUND & AIMS: The mechanisms of tissue destruction during progression of celiac disease are poorly defined. It is not clear how tissue stress and adaptive immunity contribute to activation of intraepithelial cytotoxic T cells and development of villous atrophy. We analyzed epithelial cells...

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Publicado no:Gastroenterology
Main Authors: Setty, Mala, Discepolo, Valentina, Abadie, Valérie, Kamhawi, Sarah, Mayassi, Toufic, Kent, Andrew, Ciszewski, Cezary, Maglio, Maria, Kistner, Emily, Bhagat, Govind, Semrad, Carol, Kupfer, Sonia S, Green, Peter H, Guandalini, Stefano, Troncone, Riccardo, Murray, Joseph A, Turner, Jerrold R, Jabri, Bana
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550536/
https://ncbi.nlm.nih.gov/pubmed/26001928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.05.013
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