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Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion
The mechanisms by which tumour cells metastasize and the role cell polarity proteins play in this process are not well understood. We report that Partitioning defective protein 3 (Par3) is dysregulated in metastasis in human breast cancer, and is associated with higher tumour grade and ErbB2-positiv...
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| Publicado no: | Nat Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4577246/ https://ncbi.nlm.nih.gov/pubmed/23263278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2663 |
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