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The Polarity Protein Par6 Induces Cell Proliferation and Is Overexpressed in Breast Cancer

The Polarity protein complex Par6/aPKC/Cdc42 regulates polarization processes during epithelial morphogenesis, astrocyte migration and axon specification. Others and we have demonstrated that this complex is also required for disruption of apical-basal polarity during the oncogene ErbB2-induced tran...

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Detalhes bibliográficos
Main Authors: Nolan, Marissa E., Aranda, Victoria, Lee, Sangjun, Lakshmi, Balasubramanian, Basu, Srinjan, Allred, D. Craig, Muthuswamy, Senthil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948755/
https://ncbi.nlm.nih.gov/pubmed/18922891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6567
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