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Chronophin coordinates cell leading edge dynamics by controlling active cofilin levels

Cofilin, a critical player of actin dynamics, is spatially and temporally regulated to control the direction and force of membrane extension required for cell locomotion. In carcinoma cells, although the signaling pathways regulating cofilin activity to control cell direction have been established,...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Delorme-Walker, Violaine, Seo, Ji-Yeon, Gohla, Antje, Fowler, Bruce, Bohl, Ben, DerMardirossian, Céline
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577135/
https://ncbi.nlm.nih.gov/pubmed/26324884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510945112
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