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Chronophin coordinates cell leading edge dynamics by controlling active cofilin levels

Cofilin, a critical player of actin dynamics, is spatially and temporally regulated to control the direction and force of membrane extension required for cell locomotion. In carcinoma cells, although the signaling pathways regulating cofilin activity to control cell direction have been established,...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Delorme-Walker, Violaine, Seo, Ji-Yeon, Gohla, Antje, Fowler, Bruce, Bohl, Ben, DerMardirossian, Céline
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577135/
https://ncbi.nlm.nih.gov/pubmed/26324884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510945112
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