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Inhibitors of the AAA+ Chaperone p97
It is remarkable that a pathway as ubiquitous as protein quality control can be targeted to treat cancer. Bortezomib, an inhibitor of the proteasome, was first approved by the US Food and Drug Administration (FDA) more than 10 years ago to treat refractory myeloma and later extended to lymphoma. Its...
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| Udgivet i: | Molecules |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4576884/ https://ncbi.nlm.nih.gov/pubmed/25685910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20023027 |
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