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BDNF modulates heart contraction force and long-term homeostasis through truncated TrkB.T1 receptor activation

Brain-derived neurotrophic factor (BDNF) is critical for mammalian development and plasticity of neuronal circuitries affecting memory, mood, anxiety, pain sensitivity, and energy homeostasis. Here we report a novel unexpected role of BDNF in regulating the cardiac contraction force independent of t...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Fulgenzi, Gianluca, Tomassoni-Ardori, Francesco, Babini, Lucia, Becker, Jodi, Barrick, Colleen, Puverel, Sandrine, Tessarollo, Lino
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576863/
https://ncbi.nlm.nih.gov/pubmed/26347138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201502100
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