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PAK1 modulates a PPARγ/NF-κB cascade in intestinal inflammation
P21-activated kinases (PAKs) are multifunctional effectors of Rho GTPases with both kinase and scaffolding activity. Here, we investigated the effects of inflammation on PAK1 signaling and its role in colitis-driven carcinogenesis. PAK1 and p-PAK1 (Thr423) were assessed by immunohistochemistry, immu...
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| Опубликовано в: : | Biochim Biophys Acta |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier Pub. Co
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4576212/ https://ncbi.nlm.nih.gov/pubmed/26036343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2015.05.031 |
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