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RNA-Dependent RNA Polymerases of Picornaviruses: From the Structure to Regulatory Mechanisms

RNA viruses typically encode their own RNA-dependent RNA polymerase (RdRP) to ensure genome replication within the infected cells. RdRP function is critical not only for the virus life cycle but also for its adaptive potential. The combination of low fidelity of replication and the absence of proofr...

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Détails bibliographiques
Publié dans:Viruses
Auteurs principaux: Ferrer-Orta, Cristina, Ferrero, Diego, Verdaguer, Núria
Format: Artigo
Langue:Inglês
Publié: MDPI 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576190/
https://ncbi.nlm.nih.gov/pubmed/26258787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7082829
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