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Activation mechanism of a noncanonical RNA-dependent RNA polymerase

Two lineages of viral RNA-dependent RNA polymerases (RDRPs) differing in the organization (canonical vs. noncanonical) of the palm subdomain have been identified. Phylogenetic analyses indicate that both lineages diverged at a very early stage of the evolution of the enzyme [Gorbalenya AE, Pringle F...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Garriga, Damià, Navarro, Aitor, Querol-Audí, Jordi, Abaitua, Fernando, Rodríguez, José F., Verdaguer, Núria
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154467/
https://ncbi.nlm.nih.gov/pubmed/18077388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704447104
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