Structure, Dynamics, and Allosteric Potential of Ionotropic Glutamate Receptor N-Terminal Domains

Ionotropic glutamate receptors (iGluRs) are tetrameric cation channels that mediate synaptic transmission and plasticity. They have a unique modular architecture with four domains: the intracellular C-terminal domain (CTD) that is involved in synaptic targeting, the transmembrane domain (TMD) that f...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Krieger, James, Bahar, Ivet, Greger, Ingo H.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2015
Fag:
Channels and Transporters
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576161/
https://ncbi.nlm.nih.gov/pubmed/26255587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.06.061
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