Dynamics and allosteric potential of the AMPA receptor N-terminal domain

Glutamate-gated ion channels (ionotropic glutamate receptors, iGluRs) sense the extracellular milieu via an extensive extracellular portion, comprised of two clamshell-shaped segments. The distal, N-terminal domain (NTD) has allosteric potential in NMDA-type iGluRs, which has not been ascribed to th...

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Main Authors: Sukumaran, Madhav, Rossmann, Maxim, Shrivastava, Indira, Dutta, Anindita, Bahar, Ivet, Greger, Ingo H
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049213/
https://ncbi.nlm.nih.gov/pubmed/21317871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.17
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