Potent Ex Vivo Activity of Naphthoquine and Methylene Blue against Drug-Resistant Clinical Isolates of Plasmodium falciparum and Plasmodium vivax

The 4-aminoquinoline naphthoquine (NQ) and the thiazine dye methylene blue (MB) have potent in vitro efficacies against Plasmodium falciparum, but susceptibility data for P. vivax are limited. The species- and stage-specific ex vivo activities of NQ and MB were assessed using a modified schizont mat...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Wirjanata, Grennady, Sebayang, Boni F., Chalfein, Ferryanto, Prayoga, Handayuni, Irene, Trianty, Leily, Kenangalem, Enny, Noviyanti, Rintis, Campo, Brice, Poespoprodjo, Jeanne Rini, Möhrle, Jörg J., Price, Ric N., Marfurt, Jutta
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576102/
https://ncbi.nlm.nih.gov/pubmed/26195523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00874-15
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