Expression of Plasmodium vivax crt-o Is Related to Parasite Stage but Not Ex Vivo Chloroquine Susceptibility

Chloroquine (CQ)-resistant Plasmodium vivax is present in most countries where P. vivax infection is endemic, but the underlying molecular mechanisms responsible remain unknown. Increased expression of P. vivax crt-o (pvcrt-o) has been correlated with in vivo CQ resistance in an area with low-grade...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Pava, Zuleima, Handayuni, Irene, Wirjanata, Grennady, To, Sheren, Trianty, Leily, Noviyanti, Rintis, Poespoprodjo, Jeanne Rini, Auburn, Sarah, Price, Ric N., Marfurt, Jutta
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704153/
https://ncbi.nlm.nih.gov/pubmed/26525783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02207-15
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