Contrasting Ex Vivo Efficacies of “Reversed Chloroquine” Compounds in Chloroquine-Resistant Plasmodium falciparum and P. vivax Isolates

Chloroquine (CQ) has been the mainstay of malaria treatment for more than 60 years. However, the emergence and spread of CQ resistance now restrict its use to only a few areas where malaria is endemic. The aim of the present study was to investigate whether a novel combination of a CQ-like moiety an...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Wirjanata, Grennady, Sebayang, Boni F., Chalfein, Ferryanto, Prayoga, Handayuni, Irene, Noviyanti, Rintis, Kenangalem, Enny, Poespoprodjo, Jeanne Rini, Burgess, Steven J., Peyton, David H., Price, Ric N., Marfurt, Jutta
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Susceptibility
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538531/
https://ncbi.nlm.nih.gov/pubmed/26149984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01048-15
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