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Oritavancin Pharmacokinetics and Bone Penetration in Rabbits

The pharmacokinetics and bone concentrations of oritavancin were investigated after a single intravenous dose was administered to rabbits. The pharmacokinetic profile of oritavancin in rabbits showed that it is rapidly distributed to bone tissues, with concentrations remaining stable for up to 168 h...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lehoux, Dario, Ostiguy, Valerie, Cadieux, Cordelia, Malouin, Mireille, Belanger, Odette, Far, Adel Rafai, Parr, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576084/
https://ncbi.nlm.nih.gov/pubmed/26239977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00981-15
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