Mutations in β-Lactamase AmpC Increase Resistance of Pseudomonas aeruginosa Isolates to Antipseudomonal Cephalosporins

Mutation-dependent overproduction of intrinsic β-lactamase AmpC is considered the main cause of resistance of clinical strains of Pseudomonas aeruginosa to antipseudomonal penicillins and cephalosporins. Analysis of 31 AmpC-overproducing clinical isolates exhibiting a greater resistance to ceftazidi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Berrazeg, M., Jeannot, K., Ntsogo Enguéné, Véronique Yvette, Broutin, I., Loeffert, S., Fournier, D., Plésiat, P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576058/
https://ncbi.nlm.nih.gov/pubmed/26248364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00825-15
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