Inactivation of the ampD Gene in Pseudomonas aeruginosa Leads to Moderate-Basal-Level and Hyperinducible AmpC β-Lactamase Expression

It has been shown in enterobacteria that mutations in ampD provoke hyperproduction of chromosomal β-lactamase, which confers to these organisms high levels of resistance to β-lactam antibiotics. In this study, we investigated whether this genetic locus was implicated in the altered AmpC β-lactamase...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Langaee, Taimour Yousef, Gagnon, Luc, Huletsky, Ann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89730/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.3.583-589.2000
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