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Inactivation of the ampD Gene in Pseudomonas aeruginosa Leads to Moderate-Basal-Level and Hyperinducible AmpC β-Lactamase Expression

It has been shown in enterobacteria that mutations in ampD provoke hyperproduction of chromosomal β-lactamase, which confers to these organisms high levels of resistance to β-lactam antibiotics. In this study, we investigated whether this genetic locus was implicated in the altered AmpC β-lactamase...

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Autors principals: Langaee, Taimour Yousef, Gagnon, Luc, Huletsky, Ann
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC89730/
https://ncbi.nlm.nih.gov/pubmed/10681322
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