In Vitro Activity of AZD0914, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor, against Clinically Relevant Gram-Positive and Fastidious Gram-Negative Pathogens

AZD0914, a new spiropyrimidinetrione bacterial DNA gyrase inhibitor with a novel mode of inhibition, has activity against bacterial species commonly cultured from patient infection specimens, including fluoroquinolone-resistant isolates. This study assessed the in vitro activity of AZD0914 against k...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Biedenbach, Douglas J., Huband, Michael D., Hackel, Meredith, de Jonge, Boudewijn L. M., Sahm, Daniel F., Bradford, Patricia A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Epidemiology and Surveillance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576048/
https://ncbi.nlm.nih.gov/pubmed/26195518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01016-15
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