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In Vitro Activity of AZD0914, a Novel DNA Gyrase Inhibitor, against Chlamydia trachomatis and Chlamydia pneumoniae

The in vitro activities of AZD0914, levofloxacin, azithromycin, and doxycycline against 10 isolates each of Chlamydia trachomatis and Chlamydia pneumoniae were tested. For AZD0914, the MIC(90)s for C. trachomatis and C. pneumoniae were 0.25 μg/ml (range, 0.06 to 0.5 μg/ml) and 1 μg/ml (range, 0.25 t...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kohlhoff, Stephan A., Huband, Michael D., Hammerschlag, Margaret R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249501/
https://ncbi.nlm.nih.gov/pubmed/25288086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03920-14
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