Differential Effects of Penicillin Binding Protein Deletion on the Susceptibility of Enterococcus faecium to Cationic Peptide Antibiotics

Beta-lactam antibiotics sensitize Enterococcus faecium to killing by endogenous antimicrobial peptides (AMPs) of the innate immune system and daptomycin through mechanisms yet to be elucidated. It has been speculated that beta-lactam inactivation of select E. faecium penicillin binding proteins (PBP...

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Sakoulas, George, Kumaraswamy, Monika, Nonejuie, Poochit, Werth, Brian J., Rybak, Micahel J., Pogliano, Joseph, Rice, Louis B., Nizet, Victor
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Mechanisms of Action: Physiological Effects
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576044/
https://ncbi.nlm.nih.gov/pubmed/26195528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00486-15
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