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Decreased T(FR)/T(FH) ratio in SIV-infected rhesus macaques may contribute to accumulation of T(FH) cells in chronic infection
T follicular helper cells (T(FH)) are critical for the development and maintenance of germinal centers (GC) and humoral immune responses. During chronic HIV/SIV infection T(FH) accumulate, possibly as a result of antigen persistence. The HIV/SIV-associated T(FH) expansion may also reflect lack of re...
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| Publicado en: | J Immunol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4575868/ https://ncbi.nlm.nih.gov/pubmed/26297764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402701 |
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