Impact of soluble epoxide hydrolase inhibition on early kidney damage in hyperglycemic overweight mice

This study addressed the hypothesis that inhibition of the EETs degrading enzyme soluble epoxide hydrolase affords renal protection in the early stage of diabetic nephropathy. The renal effects of the sEH inhibitor t-AUCB (10 mg/l in drinking water) were compared to those of the sulfonylurea glibenc...

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Detalhes bibliográficos
Publicado no:Prostaglandins Other Lipid Mediat
Main Authors: Roche, Clothilde, Guerrot, Dominique, Harouki, Najah, Duflot, Thomas, Besnier, Marie, Rémy-Jouet, Isabelle, Renet, Sylvanie, Dumesnil, Anaïs, Lejeune, Annie, Morisseau, Christophe, Richard, Vincent, Bellien, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575616/
https://ncbi.nlm.nih.gov/pubmed/26022136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2015.04.011
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