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Impact of soluble epoxide hydrolase inhibition on early kidney damage in hyperglycemic overweight mice

This study addressed the hypothesis that inhibition of the EETs degrading enzyme soluble epoxide hydrolase affords renal protection in the early stage of diabetic nephropathy. The renal effects of the sEH inhibitor t-AUCB (10 mg/l in drinking water) were compared to those of the sulfonylurea glibenc...

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Bibliografiske detaljer
Udgivet i:Prostaglandins Other Lipid Mediat
Main Authors: Roche, Clothilde, Guerrot, Dominique, Harouki, Najah, Duflot, Thomas, Besnier, Marie, Rémy-Jouet, Isabelle, Renet, Sylvanie, Dumesnil, Anaïs, Lejeune, Annie, Morisseau, Christophe, Richard, Vincent, Bellien, Jeremy
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575616/
https://ncbi.nlm.nih.gov/pubmed/26022136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2015.04.011
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