The IL-1β Antibody Gevokizumab Limits Cardiac Remodeling and Coronary Dysfunction in Rats With Heart Failure

This study reports preclinical data showing that the interleukin (IL)-1β modulation is a new promising target in the pathophysiological context of heart failure. Indeed, in nondiabetic Wistar and diabetic Goto-Kakizaki rats with chronic heart failure induced by myocardial infarction, administration...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Harouki, Najah, Nicol, Lionel, Remy-Jouet, Isabelle, Henry, Jean-Paul, Dumesnil, Anais, Lejeune, Annie, Renet, Sylvanie, Golding, Francesca, Djerada, Zoubir, Wecker, Didier, Bolduc, Virginie, Bouly, Muriel, Roussel, Jerome, Richard, Vincent, Mulder, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
MINI-FOCUS: INFLAMMATION IN CARDIAC INJURY
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034492/
https://ncbi.nlm.nih.gov/pubmed/30062160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2017.06.005
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