Synergistic role of ADP and Ca(2+) in diastolic myocardial stiffness

ABSTRACT: Heart failure (HF) with diastolic dysfunction has been attributed to increased myocardial stiffness that limits proper filling of the ventricle. Altered cross-bridge interaction may significantly contribute to high diastolic stiffness, but this has not been shown thus far. Cross-bridge int...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Sequeira, Vasco, Najafi, Aref, McConnell, Mark, Fowler, Ewan D, Bollen, Ilse A E, Wüst, Rob C I, dos Remedios, Cris, Helmes, Michiel, White, Ed, Stienen, Ger J M, Tardiff, Jil, Kuster, Diederik W D, van der Velden, Jolanda
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575576/
https://ncbi.nlm.nih.gov/pubmed/26096258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270354
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