Lataa...
Fanconi anemia cells with unrepaired DNA damage activate components of the checkpoint recovery process
BACKGROUND: The FA/BRCA pathway repairs DNA interstrand crosslinks. Mutations in this pathway cause Fanconi anemia (FA), a chromosome instability syndrome with bone marrow failure and cancer predisposition. Upon DNA damage, normal and FA cells inhibit the cell cycle progression, until the G2/M check...
Tallennettuna:
| Julkaisussa: | Theor Biol Med Model |
|---|---|
| Päätekijät: | , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BioMed Central
2015
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4575447/ https://ncbi.nlm.nih.gov/pubmed/26385365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12976-015-0011-4 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|