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Gene activity in primary T cells infected with HIV(89.6): intron retention and induction of genomic repeats

BACKGROUND: HIV infection has been reported to alter cellular gene activity, but published studies have commonly assayed transformed cell lines and lab-adapted HIV strains, yielding inconsistent results. Here we carried out a deep RNA-Seq analysis of primary human T cells infected with the low passa...

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Publicado en:Retrovirology
Main Authors: Sherrill-Mix, Scott, Ocwieja, Karen E., Bushman, Frederic D.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574318/
https://ncbi.nlm.nih.gov/pubmed/26377088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0205-1
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