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Administration of a CXCL12 Analog in Endotoxemia Is Associated with Anti-Inflammatory, Anti-Oxidative and Cytoprotective Effects In Vivo

BACKGROUND: The chemokine receptor CXCR4 is a multifunctional receptor which is activated by its natural ligand C-X-C motif chemokine 12 (CXCL12). As CXCR4 is part of the lipopolysaccharide sensing complex and CXCL12 analogs are not well characterized in inflammation, we aimed to uncover the systemi...

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Vydáno v:PLoS One
Hlavní autoři: Seemann, Semjon, Lupp, Amelie
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574197/
https://ncbi.nlm.nih.gov/pubmed/26375818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138389
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