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Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12

Interaction between chemokines and heparan sulfate (HS) is essential for leukocyte recruitment during inflammation. Previous studies have shown that a non-HS-binding mutant form of the inflammatory chemokine CCL7 can block inflammation produced by wild-type chemokines. This study examined the anti-i...

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Detalhes bibliográficos
Main Authors: O'Boyle, Graeme, Mellor, Paul, Kirby, John A., Ali, Simi
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791779/
https://ncbi.nlm.nih.gov/pubmed/19667120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-134643
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