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Role of 6-O-Sulfated Heparan Sulfate in Chronic Renal Fibrosis

Heparan sulfate (HS) plays a crucial role in the fibrosis associated with chronic allograft dysfunction by binding and presenting cytokines and growth factors to their receptors. These interactions critically depend on the distribution of 6-O-sulfated glucosamine residues, which is generated by gluc...

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Detalhes bibliográficos
Main Authors: Alhasan, Abd A., Spielhofer, Julia, Kusche-Gullberg, Marion, Kirby, John A., Ali, Simi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106343/
https://ncbi.nlm.nih.gov/pubmed/24878958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554691
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