Polymorphism in drug resistance genes dihydrofolate reductase and dihydropteroate synthase in Plasmodium falciparum in some states of India

BACKGROUND: Sulfadoxine-pyrimethamine (SP) combination drug is currently being used in India for the treatment of Plasmodium falciparum as partner drug in artemisinin-based combination therapy (ACT). Resistance to sulfadoxine and pyrimethamine in P. falciparum is linked with mutations in dihydropter...

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Publicado en:Parasit Vectors
Autores principales: Sharma, Divya, Lather, Manila, Mallick, Prashant K., Adak, Tridibes, Dang, Amita S., Valecha, Neena, Singh, Om P.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574150/
https://ncbi.nlm.nih.gov/pubmed/26381498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-015-1080-2
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