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Polymorphism in drug resistance genes dihydrofolate reductase and dihydropteroate synthase in Plasmodium falciparum in some states of India

BACKGROUND: Sulfadoxine-pyrimethamine (SP) combination drug is currently being used in India for the treatment of Plasmodium falciparum as partner drug in artemisinin-based combination therapy (ACT). Resistance to sulfadoxine and pyrimethamine in P. falciparum is linked with mutations in dihydropter...

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Bibliografiske detaljer
Udgivet i:Parasit Vectors
Main Authors: Sharma, Divya, Lather, Manila, Mallick, Prashant K., Adak, Tridibes, Dang, Amita S., Valecha, Neena, Singh, Om P.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574150/
https://ncbi.nlm.nih.gov/pubmed/26381498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-015-1080-2
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